Using a very precise zero-drift amplifier as a pre-amp allows for the use of a very small sense resistor in a high voltage supply line. A floating power supply regulates the voltage across the pre-amplifier on any voltage rail up to the 60V limit of the LT1787HV circuit. Overall gain of this circuit is 1000. A 1mA change in current in either direction through the 10mΩ sense resistor will produce a 10mV change in the output voltage.